THE SELFISH BRAIN THEORY
Selfish-Brain
The Selfish Brain Clinical Research Group
www.selfish-brain.net 
Recent Publications:
Ferdinand Binkofski, Professor of Neurology
Clinic of Neurology, University of Luebeck, Germany

  1. Ertelt D, Small S, Solodkin A, Dettmers C, McNamara A, Binkofski F, Buccino G (2007) Action observation has a positive impact on rehabilitation of motor deficits after stroke. Neuroimage 36 Suppl 2: T164-173.

  2. Struppler A, Binkofski F, Angerer B, Bernhardt M, Spiegel S, Drzezga A, Bartenstein P (2007) A fronto-parietal network is mediating improvement of motor function related to repetitive peripheral magnetic stimulation: A PET-H(2)O(15) study. Neuroimage 36 Suppl 2: T174-186.

  3. Binkofski F, Buccino G (2007) Therapeutic reflexion. Sci Am Mind 6/7: 78-81.

  4. Reetz K, Lencer R, Steinlechner S, Gaser C, Hagenah J, Büchel C, Petersen D, Kock N, Djarmati A, Siebner HR, Klein C, Binkofski F. Limbic and frontal cortical degeneration is associated with psychiatric symptoms in PINK1 mutation carriers. Biol. Psych. (in press).

  5. Buccino G, Baumgaertner A, Colle L, Buechel C, Rizzolatti G, Binkofski F (2007) The neural basis for understanding non-intended actions. Neuroimage 36 Suppl 2: T119-127.

  6. Baumgaertner A, Buccino G, Lange R, McNamara A, Binkofski F (2007) Polymodal conceptual processing of human biological actions in the left inferior frontal lobe. Eur J Neurosci 25: 881-889.

  7. Shikata E, McNamara A, Sprenger A, Hamzei F, Glauche V, Buchel C, Binkofski F (2007) Localization of human intraparietal areas AIP, CIP, and LIP using surface orientation and saccadic eye movement tasks. Hum Brain Mapp.

  8. Binkofski F, Fink GR, Kompf D, Rizzolatti G (2007) Introduction: Higher motor cognition - From basic neuroscience to apraxia. Neuroimage 36 Suppl 2: T1.

  9. Binkofski F, Reetz K, Blangero A (2007) Tactile agnosia and tactile apraxia: crosstalk between the action and perception streams in AIP. Behavioural and Brain Sciences 30: 2001-2002.

  10. Nagel M, Sprenger A, Hohagen F, Binkofski F, Lencer R. Cortical mechanisms of velocity adjustment during retinal and extraretinal smooth pursuit eye movements to different target velocities. Neuroimage (in press).

  11. Nagel M, Sprenger A, Nitschke M, Zapf S, Heide W, Binkofski F, Lencer R (2007) Different extraretinal neuronal mechanisms of smooth pursuit eye movements in schizophrenia: An fMRI study. Neuroimage 34: 300-309.

  12. Binkofski F, Reetz K, Gaser C, Hilker R, Buhmann C, Hedrich K, van Eimeren T, Thiel A, Büchel C, Pramstaller P, Siebner H, Klein C (2007) Morphometric fingerprint of asymptomatic Parkin and PINK1 mutation carriers in the basal ganglia. Neurology 69; 842-850.

  13. Grunewald A, Breedveld GJ, Lohmann-Hedrich K, Rohe CF, Konig IR, Hagenah J, Vanacore N, Meco G, Antonini A, Goldwurm S, Lesage S, Durr A, Binkofski F, Siebner H, Munchau A, Brice A, Oostra BA, Klein C, Bonifati V (2007) Biological effects of the PINK1 c.1366C>T mutation: implications in Parkinson disease pathogenesis. Neurogenetics 8: 103-109.

  14. Hagenah J, Reetz K, Zühlke C, Rolfs A, Binkofski F (2007) Predominant dystonia with marked cerebellar atrophy: a rare phenotype in familial dystonia. Neurology 68: 2157.

  15. McNamara A, Tegenthoff M, Dinse H, Buchel C, Binkofski F, Ragert P. (2007) Increased functional connectivity is crucial for learning novel muscle synergies. Neuroimage 35: 1211-1218.

  16. Binkofski F, Buccino G (2006) The role of ventral premotor cortex in action execution and action understanding. J Physiol Paris 99: 396-405.

  17. Binkofski F, Buccino G (2006) Der Nachahmereffekt. Gehirn & Geist 10: 41-43.

  18. Hedrich K, Hagenah J, Djarmati A, Hiller A, Lohnau T, Lasek K, Grunewald A, Hilker R, Steinlechner S, Boston H, Kock N, Schneider-Gold C, Kress W, Siebner H, Binkofski F, Lencer R, Munchau A, Klein C (2006) Clinical spectrum of homozygous and heterozygous PINK1 mutations in a large German family with Parkinson disease: role of a single hit? Arch Neurol 63: 833-838.

  19. Helmchen C, Mohr C, Erdmann C, Binkofski F, Buchel C (2006) Neural activity related to self- versus externally generated painful stimuli reveals distinct differences in the lateral pain system in a parametric fMRI study. Hum Brain Mapp 27: 755-765.

  20. Lasek K, Lencer R, Gaser C, Hagenah J, Walter U, Wolters A, Kock N, Steinlechner S, Nagel M, Zuhlke C, Nitschke MF, Brockmann K, Klein C, Rolfs A, Binkofski F (2006) Morphological basis for the spectrum of clinical deficits in spinocerebellar ataxia 17 (SCA17). Brain 129: 2341-2352.

  21. Nagel M, Sprenger A, Zapf S, Erdmann C, Kompf D, Heide W, Binkofski F, Lencer R (2006) Parametric modulation of cortical activation during smooth pursuit with and without target blanking. an fMRI study. Neuroimage 29: 1319-1325.

  22. Pisella L, Binkofski F, Lasek K, Toni I, Rossetti Y (2006) No double-dissociation between optic ataxia and visual agnosia: multiple sub-streams for multiple visuo-manual integrations. Neuropsychologia 44: 2734-2748.

  23. Binkofski F, Fink G (2005) [Apraxias.]. Nervenarzt 76: 493-512.

  24. Buccino G, Riggio L, Melli G, Binkofski F, Gallese V, Rizzolatti G (2005) Listening to action-related sentences modulates the activity of the motor system: a combined TMS and behavioral study. Brain Res Cogn Brain Res 24: 355-363.

  25. Buhmann C, Binkofski F, Klein C, Buchel C, van Eimeren T, Erdmann C, Hedrich K, Kasten M, Hagenah J, Deuschl G, Pramstaller PP, Siebner HR (2005) Motor reorganization in asymptomatic carriers of a single mutant Parkin allele: a human model for presymptomatic parkinsonism. Brain 128: 2281-2290

  26. Lencer R, Nagel M, Sprenger A, Heide W, Binkofski F (2005) Reduced neuronal activity in the V5 complex underlies smooth-pursuit deficit in schizophrenia: evidence from an fMRI study. Neuroimage 24: 1256-1259

  27. Mohr C, Binkofski F, Erdmann C, Buchel C, Helmchen C (2005) The anterior cingulate cortex contains distinct areas dissociating external from self-administered painful stimulation: a parametric fMRI study. Pain 114: 347-357

  28. Binkofski F, Seitz RJ (2004) Modulation of the BOLD-response in early recovery from sensorimotor stroke. Neurology 63(7):1223-9

  29. Binkofski F, Buccino G (2004) Motor functions of the Broca's region. Brain Lang 89(2): 362-9

  30. Binkofski F (2004) Which patients benefit? MMW Fortschr Med 146, 6

  31. Binkofski F, Buccino G, Zilles K, Fink GR (2004) Supramodal representation of objects and actions in the human inferior temporal and ventral premotor cortex. Cortex 40(1): 159-61.

  32. Lencer R, Nagel M, Sprenger A, Zapf S, Erdmann C, Heide W, Binkofski F (2004) Cortical mechanisms of smooth pursuit eye movements with target blanking. An fMRI study. Eur J Neurosci 19(5): 1430-6

  33. Stoeckel MC, Weder B, Binkofski F, Choi HJ, Amunts K, Pieperhoff P, Shah NJ, Seitz RJ (2004) Left and right superior parietal lobule in tactile object discrimination. Eur J Neurosci 19(4): 1067-72

  34. Nitschke MF, Binkofski F, Buccino G, Posse S, Erdmann C, Kompf D, Seitz RJ, Heide W (2004) Activation of cerebellar hemispheres in spatial memorization of saccadic eye movements: an fMRI study. Hum Brain Mapp 22(2): 155-64

  35. Helmchen C, Mohr C, Erdmann C, Binkofski F (2004) Cerebellar neural responses related to actively and passively applied noxious thermal stimulation in human subjects: a parametric fMRI study. Neurosci Lett 361(1-3): 237-40.

  36. Binkofski F, Ertelt D, Dettmers C, Buccino G (2004)The role of the mirror neuron system in neurorehabilitation. Neurol Rehabil 10: 1-10

  37. Buccino G, Binkofski F, Riggio L (2004) The mirror neuron system and action recognition. Brain Lang 89(2): 370-6.

  38. Binkofski F, Butler A, Buccino G, Heide W, Fink G, Freund HJ, Seitz RJ (2003) Mirror apraxia affects the peripersonal mirror space. A combined lesion and cerebral activation study. Exp Brain Res 153(2): 210-9.

  39. Helmchen C, Rambold H, Erdmann C, Mohr C, Sprenger A, Binkofski F (2003) The role of the fastigial nucleus in saccadic eye oscillations. Ann N Y Acad Sci 1994: 229-40.

  40. Helmchen C, Rambold H, Sprenger A, Erdmann C, Binkofski F (2003) Cerebellar activation in opsoclonus: an fMRI study. Neurology 61(3): 412-5.

  41. Seitz RJ, Binkofski F (2003) Modular organization of parietal lobe functions as revealed by functional activation studies. Adv Neurol 93: 281-92

  42. Shikata E, Hamzei F, Glauche V, Koch M, Weiller C, Binkofski F, Buchel C (2003) Functional properties and interaction of the anterior and posterior intraparietal areas in humans. Eur J Neurosci 17(5): 1105-10

  43. Stoeckel MC, Weder B, Binkofski F, Buccino G, Shah NJ, Seitz RJ (2003) A fronto-parietal circuit for tactile object discrimination: an event-related fMRI study. Neuroimage 19(3): 1103-14

  44. Binkofski F, Fink GR, Geyer S, Buccino G, Gruber O, Taylor GJ, Shah NJ, Seitz RJ, Zilles K, Freund HJ (2002) Neural activity in human primary motor cortex areas 4a and 4p is modulated differentially by attention to action. J Neurophysiol 88: 514-519

  45. Jaeger, M., et al. (2002) Acute low back pain with progressive sensorimotor paralysis. Differential diagnosis and therapy of acute decompression disease. Dtsch Med Wochenschr 127(22): 1188-91

  46. Binkofski F, Kunesch E, Classen J, Seitz RJ, Freund H-J (2001) Tactile apraxia: an unimodal disorder of tactile object exploration associated with parietal lesions. Brain 124: 132-144

  47. Binkofski F, Seitz RJ, Hackländer T, Pawelec D, Mau J, Freund HJ (2001) The recovery of motor function following hemiparetic stroke: A clinical and MR-morphometric strudy. Cerebrovascular Diseases 11: 273-281

  48. Heide W, Binkofski F, Seitz RJ, Posse S, Nitschke MF, Freund H-J, Kömpf, D (2001) Activation of fronto-parietal cortices during memorized triple-step sequences of saccadic eye movements: An fMRI study. Eur J Neurosci 13: 1177-1189

  49. Buccino G, Binkofski F, Fink GR, Fadiga L, Fogassi L, Gallese V, Seitz RJ, Rizzolatti G, Freund HJ (2001) Action observation activates premotor and parietal areas in a somatotopic manner: an fMRI study. Eur J Neurosci 13: 400-404

  50. Posse S, Binkofski F, Schneider F, Gembris D, Frings W, et al. (2001) A new approach to measure single-event brain activity using real-time fMRI. Hum Brain Mapp 12: 25-41

  51. Weiss P, Dohle C, Binkofski F, Freund HJ, Hefter H (2001) Motor impairment in patients with parietal lesions: disturbances of meaningless movement sequences. Neuropsychologia 39: 397-405

  52. Halsband U, Schmitt J, Weyers M, Binkofski F, Grützner G, Freund HJ (2001) Recognition and imitation of pantomimed motor acts after unilateral parietal and premotor lesions: a perspective on apraxia. Neuropsychologia 39: 200-216

  53. Binkofski F, Seitz RJ, Freund H-J (2000) Response to Altshulers letter. Ann Neurol 47: 553-554

  54. Binkofski F, Amunts K, Stephan KM, Posse S, Schormann T, Freund H-J, Zilles K, Seitz RJ (2000) Broca´s region subserves imagery of motion: a combined cytoarchitectonic and fMRI study. Human Brain Mapping 11: 273-285

  55. Gruber O, Kleinschmidt A, Binkofski F, Steinmetz H, Cramon von DY (2000) Cerebral correlates of working memory for temporal information. NeuroReport 11: 1689-93

  56. Seitz RJ, Stephan KM, Binkofski F (2000) Control of action as mediated by the human frontal lobe. Exp Brain Res 133: 71-80

  57. Binkofski F, Buccino G, Dohle C, Seitz RJ, Freund H-J (1999) Mirror agnosia and mirror ataxia constitute different parietal lobe disorders. Ann Neurol 46: 51-61

  58. Binkofski F, Buccino G, Posse S, Seitz RJ, Rizzolatti G, Freund H-J (1999) A fronto-parietal circuit for object manipulation in man. Evidence from a fMRI-Study. Eur J Neurosci 11: 3276-3286

  59. Binkofski F, Buccino G, Stephan KM, Rizzolatti G, Seitz RJ, Freund H-J (1999) Parieto-premotor network for object manipulation: evidence from neuroimaging. Exp Brain Res 128: 210-213

  60. Binkofski F, Classen J, Benecke R (1999) Stimulation of peripheral nerves using a novel magnetic coil. Muscle Nerve 22: 751-7

  61. Stephan KM, Binkofski F, Halsband U, Dohle C, Wunderlich G, Schnitzler A, Tass P, Posse S, Herzog H, Sturm V, Zilles K, Seitz RJ, Zilles K (1999) The role of ventral medial wall motor areas for bimanual coordination: a combined lesion and activation study. Brain 122: 351-368

  62. Stephan KM, Binkofski F, Posse S, Seitz RJ, Freund H-J (1999) Cerebral midline structures in bimanual coordination. Exp Brain Res 1-2: 210-3

  63. Seitz RJ, Azari N, Knorr U, Binkofski F, Herzog H, Freund H-J (1999) The role of diaschisis in stroke recovery. Stroke 30: 1844-50

  64. Seitz RJ, Binkofski F (1999) Wallerian degeneration of the pyramidal tract does not affect stroke rehabilitation. Neurology 53: 1375-6

  65. Binkofski F, Dohle C, Posse S, Hefter H, Seitz RJ, Freund H-J (1998) Human anterior intraparietal area subserves prehension. A combined lesion and fMRI study. Neurology 50: 1253-1259

  66. Binkofski F, Schnitzler A, Enck P, Frieling T, Posse S, Seitz RJ, Freund H-J (1998) Somatic and limbic activations in oesophageal distension. Ann Neurol 44: 811-815

  67. Seitz RJ, Höflich P, Binkofski F, Tellmann L, Herzog H, Freund H-J (1998) Role of the premotor cortex in recovery from middle cerebral artery infarction. Arch Neurol 55: 1081-8.